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For instance, demethylzeylasteral (DML) has been shown to suppress liver cancer stem cell tumorigenicity by inhibiting H3K9la and H3K56la, while royal jelly acid (RJA) inhibits tumor invasion, migration, proliferation, and apoptosis in HCC by targeting H3K9la and H3K14la

A significant inter-group difference in glycemic levels was noted: participants in the KD group exhibited stable glucose levels (60140 mg/dl), whereas the standard diet group showed post-meal glucose spikes for 2 hours, with baseline levels of 80100 mg/dl rising to 150180 mg/dl during meals

b , Immunoblot analysis of AMPK and pAMPK in shCtrl and shGDH1 Huh7 and H1299 cells under time course glucose starvation

These species contribute to oxidative and nitrosative stress by promoting protein nitration and nitrosation reactions, thereby affecting enzyme activity and cellular signalling pathways

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